Ibuprofen, Etc. Linked to Male Infertility, Low Testosterone, Etc.

July 27, 2018

Ibuprofen linked to male infertility, study finds…Advil and Motrin are two brand names for ibuprofen, an over-the-counter pain reliever…early experiments, published in several papers, showed that when taken during pregnancy, all three of these mild medicines affected the testicles of male babies…All three drugs then are ‘anti-androgenic,’ meaning they disrupt male hormones, explained David M. Kristensen, study co-author and a senior scientist in the Department of Neurology at Copenhagen University Hospital…ibuprofen is often taken by athletes, including Olympians…before an event to prevent pain…For the men taking ibuprofen, within 14 days, their luteinizing hormones — which are secreted by the pituitary gland and stimulate the testicles to produce testosterone — became coordinated with the level of ibuprofen circulating in their blood. At the same time, the ratio of testosterone to luteinizing hormones decreased, a sign of dysfunctional testicles…This hormonal imbalance produced compensated hypogonadism, a condition associated with impaired fertility, depression and increased risk for cardiovascular events, including heart failure and stroke…Erma Z. Drobnis, an associate professional practice professor of reproductive medicine and fertility at the University of Missouri, Columbia, noted that most drugs are not evaluated for their effects on human male fertility before marketing…“There is evidence that some medications are particularly harmful to the male reproductive system, including testosterone, opioids, antidepressants, antipsychotics, immune modulators and even the over-the-counter antacid cimetidine (Tagamet),’ she said…”
(https://fox8.com/2018/01/09/ibuprofen-linked-to-male-infertility-study-finds/)

 

 

 

 

 

 

 

 

 

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