Lack of protein in diet lowers male fertility, affects offspring
August 29, 2018
"New research has shown that a lack of protein in a father's diet affects sperm quality which can have a direct impact on the long-term health of their offspring…The study - 'Paternal diet programs offspring health through sperm - and seminal plasma-specific pathways in mice' - carried out at the University of Nottingham fed male mice a poor quality diet which resulted in their offspring becoming over weight, with symptoms of type 2 diabetes and reduced expression of genes which regulate the metabolism of fat…The study, carried out on mice, found that males fed a low-protein diet produced sperm with fewer chemical tags on their DNA that regulate gene expression than mice fed a normal diet… Kevin Sinclair, Professor of Developmental Biology in the School of Biosciences, who collaborated on this study said: ‘It is important to recognise that sperm contribute more than just half of the genes that make up a child. During natural conception sperm deposited in the female reproductive tract are bathed in seminal plasma which can in itself influence pregnancy outcomes. Our study shows that the composition of seminal plasma can be altered by father's diet, and that this can also influence offspring wellbeing’.” (EurekAlert, Aug. 29, 2018)
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